Read more: http://www.laserfocusworld.com/articles/print/volume-52/issue-04/newsbreaks/femtosecond-lasers-weld-neurons-back-together.html?cmpid=LFWLasersSources04212016&eid=295605589&bid=1382967
Thursday, April 21, 2016
Femtosecond lasers weld neurons back together
Intact neuronal cells consisting of soma (the main cell body),
dendrites (structures that branch off the soma), and the axon (a long
extension from the cell body that connects to other soma, dendrites, or
axons) process and transfer information via electrical impulses and
chemical signals. Of course, when these neuronal pathways are disrupted, communication is broken, causing the muscles normally innervated by these synaptic pathways to atrophy and/or die.

Until now, it was not possible to reconnect neuronal tissue. But thanks to ongoing applications development for ultrafast lasers,
researchers at the University of Alberta (Edmonton, AB, Canada) have
used a near-infrared femtosecond laser with 1.7 (± 0.08) × 1012 W/cm2
intensity and ± 0.5 μm aiming accuracy to perform "hemifusion" of
healthy soma and axons. Through ultrafast multiphoton and avalanche
ionization processes, the laser pulses induce molecular rearrangement of
the phospholipid bilayers, allowing photo-induced ions and electrons to
cross over to the central nonpolar region of the phospholipid bilayer
and break the bonds of the fatty acid tails, after which the ionized
phospholipid molecules seek an equilibrium state and form new bonds with
nearby ions. This cross-linking process forms a strong, shared
phospholipid bilayer or hemifused membrane-an important implication for
potential studies into neuronal regeneration and repair. Reference: N. Katchinskiy et al., Sci. Rep., 6, 20529 (Feb. 5, 2016).
Read more: http://www.laserfocusworld.com/articles/print/volume-52/issue-04/newsbreaks/femtosecond-lasers-weld-neurons-back-together.html?cmpid=LFWLasersSources04212016&eid=295605589&bid=1382967
Read more: http://www.laserfocusworld.com/articles/print/volume-52/issue-04/newsbreaks/femtosecond-lasers-weld-neurons-back-together.html?cmpid=LFWLasersSources04212016&eid=295605589&bid=1382967
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